Journal
JOURNAL OF COMBINATORIAL CHEMISTRY
Volume 10, Issue 6, Pages 851-857Publisher
AMER CHEMICAL SOC
DOI: 10.1021/cc800070a
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Funding
- RS Wolfson Fellowship
- EPSRC
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A scalable method for the preparation of 4,5-disubstituted thiazoles and imidazoles as distinct regioisomeric products using a modular flow microreactor has been devised. The process makes use of microfluidic reaction chips and packed immobilized-reagent columns to effect bifurcation of the reaction pathway.
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