Journal
JOURNAL OF COMBINATORIAL CHEMISTRY
Volume 10, Issue 1, Pages 88-93Publisher
AMER CHEMICAL SOC
DOI: 10.1021/cc700178a
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This manuscript details the construction of a fully automated flow hydrogenation apparatus for use in high-throughput organic synthesis. The instrument comprises of a Bohdan robot platform coupled with a ThalesNano H-cube hydrogenator and a series of solvent valves and pumping mechanisms. Using this instrument, we have been able to fully automate a number of key transformations that could not otherwise be conveniently undertaken in a high-throughput manner.
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