Journal
JOURNAL OF COLLOID AND INTERFACE SCIENCE
Volume 366, Issue 1, Pages 130-134Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.jcis.2011.09.082
Keywords
Glucose biosensor; CdS nanorod arrays; Electron transfer; Bioelectronics
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Funding
- National Basic Research Program of China (973 Program) [2007CB936300]
- NSFC [30870626]
- Key Laboratory of MEMS of Ministry of Education, Southeast University [2008DFA51180]
- State Key Laboratory of Bioelectronic, Southeast University
- Scientific Research Foundation of Nanjing University of Posts and Telecommunications [NY210083]
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Well-defined hexangularly faced CdS nanorod arrays have been grown directly on a conductive ITO glass via a facile one-step and non-template hydrothermal approach. Gold nanoparticles were decorated onto the nanorods to enhance the electron transfer process of electrode. Glucose oxidase (GOD) was then immobilized on the CdS through crosslinking with chitosan (CS), which resulted in a glucose biosensor with high enzyme loading and excellent sensitivity. Such a chitosan-encapsulated GOD-based biosensor revealed a relatively rapid response time of less than 50 s, and an approximate linear detection range of glucose concentration, from 50 to 500 mu mol L(-1) with a detection limit of 38 mu mol L(-1) and an electrode sensitivity of 5.9 mu A mM(-1). (C) 2011 Elsevier Inc. All rights reserved.
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