Journal
JOURNAL OF CLINICAL VIROLOGY
Volume 58, Issue 1, Pages 321-324Publisher
ELSEVIER
DOI: 10.1016/j.jcv.2013.05.001
Keywords
Herpetic keratitis; Immunocompetent patient; Resistance to acyclovir; Phenotypic and genotypic antiviral resistance assay
Categories
Funding
- Association pour la Recherche sur les Infections Virales (ARIV)
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Herpes simplex virus type 1 (HSV-1) is a leading cause of corneal blindness. Acyclovir (ACV) constitutes the standard treatment of HSV infections including herpetic keratitis (HK). HSV resistance to ACV is mainly described in immunocompromised patients. We describe two cases of ACV-resistant corneal HSV-1 in immunocompetent individuals with recurrent HK. (C) 2013 Elsevier B. V. All rights reserved.
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