Journal
JOURNAL OF CLINICAL VIROLOGY
Volume 41, Issue 1, Pages 34-37Publisher
ELSEVIER
DOI: 10.1016/j.jcv.2007.10.025
Keywords
human bocavirus; airway; infection; multiple; children
Categories
Ask authors/readers for more resources
Background: Human bocavirus (HBoV) was recently discovered in children with acute respiratory tract infections. We have included a PCR for HBoV in a study on airway infections in children. Objectives: To study the occurrence of HBoV in Norwegian children, and to evaluate the results of a semiquantitive PCR. Study design: During a 4-month period in the winter season 2006/2007 we collected nasopharyngeal aspirations from children who were admitted to the Department of Pediatrics. All samples were examined for 17 agents with real-time PCR. Results: HBoV was detected in 45 of 376 samples (12%). The occurrence of HBoV was stable during the study period. Multiple viral infections were present in 78% of the samples (42% double, 20% triple and 16% quadruple infections). RS-virus, enterovirus and human metapneumovirus were the most frequently codetected agents. In samples with a high load for HBoV, significantly fewer multiple infections were found than in the other samples. Eighty-eight percent of the 25 patients with HBoV recorded as either the only or the dominating virus, and 50% of the other patients, had lower respiratory tract infection. The difference was statistically significant. Conclusions: HBoV was frequently detected in nasopharyngeal aspirates from children with airway infections in Norway. Multiple viral infections were common among the HBoV-infected patients. Semiquantitive PCR results may be useful for interpretation of clinical relevance. (C) 2007 Elsevier B.V All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available