Effectiveness of a calcium sodium phosphosilicate containing prophylaxis paste in reducing dentine hypersensitivity immediately and 4 weeks after a single application: a double-blind randomized controlled trial

Aims The aim of this single-site, randomized, controlled, double-blind, 3-arm parallel study was to determine the effectiveness of a prophylaxis paste containing 15% calcium sodium phosphosilicate (CSPS; NovaMin (R)) with and without fluoride in reducing dentine hypersensitivity immediately after a single application and 28days following dental scaling and root planing. Materials & Methods Overall, 151 subjects were enrolled in this study. All subjects received a scaling and root planing procedure followed by a final prophylaxis step using one of three different prophylaxis pastes: Test-A (15% NovaMin (R) and NaF), Test-B (15% NovaMin (R)) and a control. Dentine hypersensitivity was assessed by tactile stimulus (Yeaple Probe (R)) and by air blast (Schiff scale) at baseline, immediately after and 28days after a prophylaxis procedure. One hundred and forty-nine subjects completed the study. Results Subjects having received the test prophylaxis pastes showed statistically lower (anova, p<0.05) dentine hypersensitivity compared with the control group immediately after the prophylaxis procedure (Yeaple Probe (R): Test-A=20.9 +/- 12.6, Test-B=22.7 +/- 12.9, Control=11.2 +/- 3.1; Schiff score: Test-A=1.1 +/- 0.6, Test-B=1.1 +/- 0.6, Control=2.0 +/- 0.7) and after 28days (Yeaple probe: Test-A=21.5 +/- 11.9, Test-B=20.6 +/- 11.3, Control=11.8 +/- 6.0; Schiff score: Test-A=1.0 +/- 0.6, Test-B=1.0 +/- 0.6, Control=2.0 +/- 0.7). Conclusions In conclusion, the single application of both fluoridated and non-fluoridated prophylaxis pastes containing 15% CSPS (NovaMin (R)) provided a significant reduction of dentine hypersensitivity up to at least 28days.