Journal
JOURNAL OF CLINICAL PERIODONTOLOGY
Volume 40, Issue 1, Pages 90-98Publisher
WILEY-BLACKWELL
DOI: 10.1111/jcpe.12027
Keywords
bone regeneration; bone substitute; cone-beam CT; graft material; human; RCT; socket preservation
Categories
Funding
- Clinic of Fixed and Removable Prosthodontics and Dental Material Science
- Clinic of Preventive Dentistry, Periodontology and Cariology
- Center of Dental Medicine, University of Zurich, Zurich, Switzerland
- Geistlich Pharma AG, Wolhusen, Switzerland
- Degradable Solutions AG, Schlieren, Switzerland
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Objective To evaluate the radiographic changes of the alveolar ridge following application of different ridge preservation techniques 6 months after tooth extraction. Materials and Methods Four treatment modalities were randomly assigned in 40 patients: beta-tricalcium-phosphate-particles with polylactid coating (beta-TCP), demineralized bovine bone mineral with 10% collagen covered with a collagen matrix (DBBM-C/CM), DBBM-C covered with an autogenous soft-tissue graft (DBBM-C/PG) and spontaneous healing (control). Cone-beam computed tomography scans were performed after treatment and 6 months later. Results After 6 months, the vertical changes ranged between -0.6 mm (-10.2%) for control and a gain of 0.3 mm (5.6%) for DBBM-C/PG on the lingual side, and between -2.0 mm (-20.9%) for beta-TCP and a gain of 1.2 mm (8.1%) for DBBM-C/PG on the buccal side. The most accentuated ridge width changes were recorded 1 mm below the crest: -3.3 mm (-43.3%, C), -6.1 mm (-77.5%, beta-TCP), -1.2 mm (-17.4%, DBBM-C/CM) and -1.4 mm (-18.1%, DBBM-C/PG). At all three levels, DBBM-C with either CM or PG was not significantly differing (p > 0.05), while most other differences between the groups reached statistical significance (p < 0.05). Conclusions Application of DBBM-C, covered with CM or PG, resulted in less vertical and horizontal changes of the alveolar ridge as compared with controls 6 months after extraction.
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