Journal
JOURNAL OF CLINICAL PERIODONTOLOGY
Volume 36, Issue 10, Pages 823-829Publisher
WILEY
DOI: 10.1111/j.1600-051X.2009.01462.x
Keywords
capsular serotypes; cytokines; dendritic cells; Porphyromonas gingivalis
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Funding
- Spanish Ministry of Science and Education [SAF2007-63631]
- Spanish Ministry of Health [FIS-060181]
- Chilean Government [CONICYT-26080046]
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P>Aim Capsular polysaccharides play an important role in the virulence of Gram-positive and Gram-negative bacteria. In Porphyromonas gingivalis, six serotypes have been described based on capsular antigenicity and its pathogenicity has been correlated both in vitro and in animal models. This study aimed to investigate the differential response of human dendritic cells (DCs) when stimulated with different P. gingivalis capsular serotypes. Materials and Methods Using different multiplicity of infection (MOI) of the encapsulated strains K1-K6 and the non-encapsulated K
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