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Fibrosing organising pneumonia

Journal

JOURNAL OF CLINICAL PATHOLOGY
Volume 66, Issue 10, Pages 875-881

Publisher

BMJ PUBLISHING GROUP
DOI: 10.1136/jclinpath-2012-201342

Keywords

Lung; Inflammation; fibrosis

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Organising pneumonia (otherwise referred to as bronchiolitis obliterans organising pneumonia) is characterised histologically by plugs of granulation tissue, which are present predominantly within small airways, alveolar ducts and peri-bronchiolar alveoli. This pattern is not specific for any disorder or cause, but is one type of inflammatory response to pulmonary injury, which may be seen in a wide variety of clinical conditions. Typically, organising pneumonia responds very well to corticosteroid treatment; however, a small percentage of patients appear to develop progressive fibrosis.

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