Journal
NEW ENGLAND JOURNAL OF MEDICINE
Volume 373, Issue 2, Pages 154-162Publisher
MASSACHUSETTS MEDICAL SOC
DOI: 10.1056/NEJMoa1415627
Keywords
-
Categories
Funding
- Federal Ministry of Food and Agriculture (Germany)
- European Union ERA-NET project EpiSeq [2811ERA094]
- Federal Ministry of Food and Agriculture [Germany]
- [FV E/U2AD/CF512/DF557 META-InfRisk]
Ask authors/readers for more resources
Between 2011 and 2013, three breeders of variegated squirrels (Sciurus variegatoides) had encephalitis with similar clinical signs and died 2 to 4 months after onset of the clinical symptoms. With the use of a metagenomic approach that incorporated next-generation sequencing and real-time reverse-transcriptase quantitative polymerase chain reaction (RT-qPCR), the presence of a previously unknown bornavirus was detected in a contact squirrel and in brain samples from the three patients. Phylogenetic analyses showed that this virus, tentatively named variegated squirrel 1 bornavirus (VSBV-1), forms a lineage separate from that of the known bornavirus species. (Funded by the Federal Ministry of Food and Agriculture [Germany] and others.)
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available