Journal
JOURNAL OF CLINICAL NEUROSCIENCE
Volume 17, Issue 12, Pages 1581-1582Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.jocn.2010.03.028
Keywords
Brain neoplasms; Meningeal carcinomatosis; Meningioma; Rhabdoid tumor
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Rhabdoid meningiomas are rare, aggressive tumours of the meninges that have a generally poor prognosis. We report a 49-year-old man with a background history of sarcoidosis who presented with nausea and vomiting. Imaging showed generalised leptomeningeal and subependymal enhancement suggestive of chronic meningitis. He had multiple lumbar punctures and a brain biopsy, none of which led to a pathological diagnosis. He died within months, and a postmortem examination was performed. At this stage, a diagnosis of rhabdoid meningioma was made. The clinical and radiological presentation of rhabdoid meningioma as a diffuse leptomeningeal process without a mass lesion is unique. All other published cases of rhabdoid meningioma have been of a discrete lesion. This highlights the importance of a tissue diagnosis in patients where the imaging is non-specific. A brief review of rhabdoid meningioma follows. Crown Copyright (C) 2010 Published by Elsevier Ltd. All rights reserved.
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