Journal
JOURNAL OF CLINICAL NEUROSCIENCE
Volume 16, Issue 12, Pages 1694-1696Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.jocn.2009.05.013
Keywords
Malignant; Prolactinoma; Temozolomide
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We report a 64-year-old male who presented to our department in 2007 with bitemporal hemianopia secondary to a large recurrent pituitary prolactinoma in the sellar region and metastatic deposits elsewhere in his neuraxis. He underwent a transphenoidal excision of the large pituitary adenoma which was uncomplicated, although lie did suffer from diabetes insipidus post-operatively. He had initially been diagnosed with prolactinoma some years before and had undergone multiple craniotomies to debulk recurrent metastatic lesions. As the patient had already undergone radiotherapy in the past, a novel approach to adjuvant therapy was necessary and he was started on a Course of oral chemotherapy, temozolomide, with good results. Crown Copyright (C) 2009 Published by Elsevier Ltd. All rights reserved.
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