Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 51, Issue 5, Pages 1611-1613Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00519-13
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- Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH)
- Bill and Melinda Gates Foundation
- Abbott Molecular Diagnostics
- BD Diagnostics
- Beckman Coulter
- Cepheid
- Roche Molecular Diagnostics
- Gen-Probe Hologic
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The GeneXpert CT/NG assay (GeneXpert) and the Abbott m2000 RealTime CT (m2000) assay were compared to Amplicor for detecting ocular Chlamydia trachomatis. Discordant specimens were tested by the Aptima CT assay. The m2000 assay sensitivity was 100% (95% confidence interval [CI], 90% to 100%), and specificity was 98.46% (95% CI, 95.2% to 99.2%); GeneXpert sensitivity was 100% (95% CI, 90% to 100%), and specificity was 100% (95% CI, 98.1% to 100%). The m2000 and GeneXpert assays appear to perform as well as the Amplicor assay.
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