Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 51, Issue 5, Pages 1359-1366Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.03105-12
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- Bruker Daltonics
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Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS)-based identification is being adopted by clinical laboratories for routine identification of microorganisms. To date, the majority of studies have focused on the performance and optimization of MALDI-TOF MS for the identification of bacterial isolates. We review recent literature describing the use of MALDI-TOF MS for the routine identification of a variety of yeasts and yeast-like isolates. Specific topics include the effect of optimized or streamlined extraction methods, modified scoring thresholds, expanded reference libraries, and the possibility of conducting antifungal susceptibility testing using MALDI-TOF MS.
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