Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 50, Issue 7, Pages 2479-2483Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00224-12
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- Universita Cattolica del Sacro Cuore
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Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) was evaluated for testing susceptibility to caspofungin of wild-type and fks mutant isolates of Candida and Aspergillus. Complete essential agreement was observed with the CLSI reference method, with categorical agreement for 94.1% of the Candida isolates tested. Thus, MALDI-TOF MS is a reliable and accurate method to detect fungal isolates with reduced caspofungin susceptibility.
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