Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 50, Issue 10, Pages 3374-3377Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.01121-12
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Funding
- Interreg IVa part of a Dutch-German cross-border network [III-1-02=73, III-2-03=025]
- European Commission
- German Federal States of Nordrhein-Westfalen and Niedersachsen
- Dutch province of Overijssel
- Dutch province of Gelderland
- Dutch province of Limburg
- Bundesministerium fur Bildung und Forschung (BMBF), Germany Interdisciplinary Research Network MedVet-Staph [01KI1014A]
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In this study, 18 methicillin-resistant Staphylococcus aureus (MRSA) isolates harboring staphylococcal cassette chromosome mec (SCCmec) type XI, recovered in the Dutch-German Euregio, were characterized by DNA microarrays. In contrast to previous data, we found two MRSA strains of different clonal lineages possessing SCCmec XI that carried important virulence determinants. The worrisome emergence of such toxigenic MRSA strains raises concerns that MRSA strains with enhanced virulence potential and impaired detectability by standard molecular assays may spread in Europe.
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