Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 50, Issue 4, Pages 1471-1474Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.05793-11
Keywords
-
Categories
Funding
- National Major Science and Technology Project for the Prevention and Treatment of AIDS and Viral Hepatitis and Other Major Infectious Diseases [2008ZX10003-005]
Ask authors/readers for more resources
The presence of heteroresistance was represented by 23% of 235 fluoroquinolone (FQ)-resistant Mycobacterium tuberculosis isolates in Beijing, China, from 2008 to 2010. The main mechanism of FQ heteroresistance is due to the segregation of a single M. tuberculosis strain in patients; the majority of isolates with multidrug-resistant tuberculosis contained a mixture of bacterial subpopulations consisting of various mutant types, suggesting that the improper use of FQ is the major cause of FQ resistance.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available