4.7 Article

Quinolone-Resistant Escherichia coli O127a:K63 Serotype with an Extended-Spectrum-Beta-Lactamase Phenotype from a Food Poisoning Outbreak in China

Journal

JOURNAL OF CLINICAL MICROBIOLOGY
Volume 50, Issue 7, Pages 2450-2451

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00276-12

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Funding

  1. Mega-projects of Science and Technology Research [2012ZX10004215, 2012ZX10004-801, 2011ZX10004-001, 2009ZX10004-205]
  2. National Natural Science Foundation of China [21105122, 81001267]
  3. Beijing Science and Technology Nova Program [2010B067]

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We report an atypical enteropathogenic Escherichia coli O127a:K63 strain with resistance to quinolones and extended-spectrum cephalosporins isolated from a 2010 food poisoning outbreak involving 112 adults in China. Two resistance genes [bla(CTX-M-15), aac(6')-Ib-c] and five mutations (two in gyrA, two in parC, one in parE) coexisted in this enteropathogenic E. coli strain.

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