4.7 Article

Toxin Detection in Patients' Sera by Mass Spectrometry during Two Outbreaks of Type A Botulism in France

Journal

JOURNAL OF CLINICAL MICROBIOLOGY
Volume 50, Issue 12, Pages 4091-4094

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.02392-12

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  1. IP
  2. CEA

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In two outbreaks of food-borne botulism in France, Clostridium botulinum type A was isolated and characterized from incriminated foods. Botulinum neurotoxin type A was detected in the patients' sera by mouse bioassay and in vitro endopeptidase assay with an immunocapture step and identification of the cleavage products by mass spectrometry.

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