Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 50, Issue 11, Pages 3726-3728Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00620-12
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Pyrazinamide (PZA) is an important component of first-line therapy for the treatment of tuberculosis. Here, we evaluate targeted gene sequencing as a supplement to phenotypic PZA susceptibility testing of Mycobacterium tuberculosis. Routine sequencing of pncA, but not rpsA, is effective for verification of PZA susceptibility results.
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