Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 49, Issue 4, Pages 1646-1649Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.01990-10
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Funding
- Japanese Ministry of Education, Culture, Sports, Science and Technology [21791638]
- NIH [AI021458]
- WCU
- Grants-in-Aid for Scientific Research [21791638] Funding Source: KAKEN
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Pneumococcal phase variation of 37 middle ear and 31 nasopharyngeal isolates obtained from children with acute otitis media was examined in the absence of intervening culture. The fraction of the opaque colonies was significantly higher in middle ear isolates than in nasopharyngeal isolates. The difference is probably the result of the pneumococci adapting to differential selective environments.
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