4.7 Article

Discriminating Lyme Neuroborreliosis from Other Neuroinflammatory Diseases by Levels of CXCL13 in Cerebrospinal Fluid

Journal

JOURNAL OF CLINICAL MICROBIOLOGY
Volume 49, Issue 5, Pages 2027-2030

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AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00084-11

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liosis (LNB). Levels of intrathecal CXCL13 were determined for 58 LNB patients and 210 controls; sensitivity was 88% and specificity was 89% (cutoff, 250 pg of CXCL13/ml of CSF). Elevated levels of CXCL13 can aid in the diagnosis of LNB, but levels should be interpreted with care.

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