4.7 Article

Real-Time Detection of blaKPC in Clinical Samples and Surveillance Specimens

Journal

JOURNAL OF CLINICAL MICROBIOLOGY
Volume 49, Issue 9, Pages 3338-3339

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00268-11

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Funding

  1. Wyeth Pharmaceuticals (recently acquired by Pfizer, Inc.)
  2. NIH [1R56AI090844-01 ARRA]
  3. Department of Pathology & Laboratory Medicine at NorthShore University Health System

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A real-time PCR assay was developed targeting the bla(KPC) responsible for Klebsiella pneumoniae carbapenemase (KPC)-mediated carbapenem resistance and was validated for testing colonies or enrichment broth cultures. The assay accurately detects KPC-containing strains with high analytical specificity and sensitivity.

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