4.7 Article

The Geographic Origin of Helicobacter pylori Influences the Association of the homB Gene with Gastric Cancer

Journal

JOURNAL OF CLINICAL MICROBIOLOGY
Volume 50, Issue 3, Pages 1082-1085

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.06293-11

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Funding

  1. National Research Foundation of South Korea (NRF)
  2. Ministry of Education, Science, and Technology [R13-2003-013-04002-0]

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We found that South Korean Helicobacter pylori isolates predominantly carry homB at locus B and that there is no association between the homB allele and the cagA allele or the development of gastric cancer within this population. Uniquely, several East Asian strains carried multiple copies of the hom genes.

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