4.7 Article

Real-Time Analysis of Mucosal Flora in Patients with Inflammatory Bowel Disease in India

Journal

JOURNAL OF CLINICAL MICROBIOLOGY
Volume 48, Issue 11, Pages 4279-4282

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.01360-10

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Funding

  1. Department of Science and Technology, Government of India
  2. University Grants Commission, New Delhi, India
  3. Indian Council of Medical Research, New Delhi, India

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Mucosa-associated bacterial flora from control individuals and inflammatory bowel disease (IBD) patients were evaluated by real-time analysis using 16S rRNA-based genus-specific primers. Our data show a clear delineation in concentration of bacteria between the predominating and subdominating genera under disease conditions, indicating that the subsets of bacteria participating in the pathogenesis of ulcerative colitis (UC) and Crohn's disease (CD) are likely to be different.

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