4.7 Article

Population Structure Dynamics of Mycobacterium tuberculosis Beijing Strains during Past Decades in Japan

Journal

JOURNAL OF CLINICAL MICROBIOLOGY
Volume 47, Issue 10, Pages 3340-3343

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.01061-09

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Funding

  1. JSPS [20249007]
  2. United States-Japan Cooperative Medical Science Program
  3. Grants-in-Aid for Scientific Research [20249007] Funding Source: KAKEN

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We used 909 strains to compare the population structures of the Mycobacterium tuberculosis Beijing family between different birth-year cohorts in Japan. The results revealed that the spread of a modern sublineage that has high transmissibility is currently increasing, while the spread of an ancient sublineage, STK, has significantly decreased in younger generations.

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