Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 47, Issue 5, Pages 1556-1558Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.01657-08
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Funding
- Ministry of Science, Technology and Innovation, Malaysia [12-02-03-2033]
- University Malaya, Malaysia [PJP F0186/2007A]
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A patient with a clonal infection of Burkholderia pseudomallei had subpopulations with ceftazidime and amoxicillin-clavulanate susceptibilities that differed among the clinical specimens. Resistance was associated with a novel Cys69Tyr substitution in the Ambler class A beta-lactamase. Susceptibility testing of multiple colony variants from different sites should be performed for patients with culture-confirmed melioidosis.
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