4.7 Article

Clinical and Molecular Epidemiology of Human Parainfluenza Virus 4 Infections in Hong Kong: Subtype 4B as Common as Subtype 4A

Journal

JOURNAL OF CLINICAL MICROBIOLOGY
Volume 47, Issue 5, Pages 1549-1552

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00047-09

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Funding

  1. Committee of Research and Conference
  2. University Development Fund
  3. HKU Special Research Achievement Award
  4. The University of Hong Kong
  5. Croucher Senior Medical Research Fellowship [20062007]
  6. HKSAR Research
  7. Control of Infectious Diseases of the Health
  8. Welfare and Food Bureau

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In this 1-year study, 35 (1.2%) of 2,912 nasopharyngeal aspirates were positive for human parainfluenza virus 4 (HPIV4) by reverse transcription-PCR. Patients with HPIV4 infection were mainly young children and immunocompromised adults. In contrast to the reported predominance of HPIV4A infection, molecular subtyping revealed that 15 (44%) cases were caused by HPIV4B.

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