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The CB1 cannabinoid receptor is the major cannabinoid receptor at excitatory presynaptic sites in the hippocampus and cerebellum
Y Kawamura et al.
JOURNAL OF NEUROSCIENCE (2006)
G protein βγ-subunits activated by serotonin mediate presynaptic inhibition by regulating vesicle fusion properties
H Photowala et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients - RIO-North America: A randomized controlled trial
F Pi-Sunyer et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2006)
The emerging role of the endocannabinoid system in endocrine regulation and energy balance
U Pagotto et al.
ENDOCRINE REVIEWS (2006)
A tale of two cannabinoids: The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol
E Russo et al.
MEDICAL HYPOTHESES (2006)
Chemical constituents of marijuana: The complex mixture of natural cannabinoids
MA ElSohly et al.
LIFE SCIENCES (2005)
Δ9-Tetrahydrocannabinol-induced desensitization of cannabinoid-mediated inhibition of synaptic transmission between hippocampal neurons in culture
DJ Lundberg et al.
NEUROPHARMACOLOGY (2005)
Dual modulation of endocannabinoid transport and fatty acid amide hydrolase protects against excitotoxicity
DA Karanian et al.
JOURNAL OF NEUROSCIENCE (2005)
Agonistic properties of cannabidiol at 5-HT1a receptors
EB Russo et al.
NEUROCHEMICAL RESEARCH (2005)
Epileptic seizures and epilepsy: Definitions proposed by the International League against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)
RS Fisher et al.
EPILEPSIA (2005)
Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation
Jared Ehrhart et al.
JOURNAL OF NEUROINFLAMMATION (2005)
Neuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on β-amyloid-induced toxicity in PC12 cells
T Iuvone et al.
JOURNAL OF NEUROCHEMISTRY (2004)
The interaction of cannabinoids and opioids on pentylenetetrazole-induced seizure threshold in mice
H Shafaroodi et al.
NEUROPHARMACOLOGY (2004)
Prefrontal cortex stimulation induces 2-arachidonoyl-glycerol-mediated suppression of excitation in dopamine neurons
M Melis et al.
JOURNAL OF NEUROSCIENCE (2004)
Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients
DT Wade et al.
MULTIPLE SCLEROSIS (2004)
Marijuana use and epilepsy - Prevalence in patients of a tertiary care epilepsy center
DW Gross et al.
NEUROLOGY (2004)
Signaling pathways involved in the development of cannabinoid tolerance
BR Martin et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2004)
Selective antiepileptic effects of N-palmitoylethanolamide, a putative endocannabinoid
AH Sheerin et al.
EPILEPSIA (2004)
Neuroprotective effect of(-)Δ9-tetrahydrocannabinol and cannabidiol in N-methyl-D-aspartate-induced retinal neurotoxicity -: Involvement of peroxynitrite
AB El-Remessy et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
CB1 cannabinoid receptors and on-demand defense against excitotoxicity
G Marsicano et al.
SCIENCE (2003)
Brief presynaptic bursts evoke synapse-specific retrograde inhibition mediated by endogenous cannabinoids
SP Brown et al.
NATURE NEUROSCIENCE (2003)
The endogenous cannabinoid system regulates seizure frequency and duration in a model of temporal lobe epilepsy
MJ Wallace et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Long-term plasticity of endocannabinoid signaling induced by developmental febrile seizures
K Chen et al.
NEURON (2003)
Clinically important drug interactions in epilepsy: interactions between antiepileptic drugs and other drugs
PN Patsalos et al.
LANCET NEUROLOGY (2003)
The effects of Δ9-tetrahydrocannabinol physical dependence on brain cannabinoid receptors
CS Breivogel et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2003)
The molecular logic of endocannabinoid signalling
D Piomelli
NATURE REVIEWS NEUROSCIENCE (2003)
Comparison of smoked marijuana and oral Δ9-tetrahydrocannabinol in humans
CL Hart et al.
PSYCHOPHARMACOLOGY (2002)
Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity
MJ Wallace et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2002)
Effect of chronic administration of R-(+)-[2,3-dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazinyl]-(1-naphthalenyl)methanone mesylate (IN55,212-2) or Δ9-tetrahydrocannabinol on cannabinoid receptor adaptation in mice
LJ Sim-Selley et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Role of CB1 and CB2 receptors in the inhibitory effects of cannabinoids on lipopolysaccharide-induced nitric oxide release in astrocyte cultures
F Molina-Holgado et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance
T Sugiura et al.
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2002)
Cannabinoids and brain injury: therapeutic implications
R Mechoulam et al.
TRENDS IN MOLECULAR MEDICINE (2002)
SR 141716A prevents Δ9-tetrahydrocannabinol-induced spatial learning deficit in a Morris-type water maze in mice
GE Da Silva et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2002)
Refractory epilepsy: a progressive, intractable but preventable condition?
P Kwan et al.
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY (2002)
Modulation of transmitter release via presynaptic cannabinoid receptors
E Schlicker et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2001)
Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide
T Bisogno et al.
BRITISH JOURNAL OF PHARMACOLOGY (2001)
Alcohol and marijuana: Effects on epilepsy and use by patients with epilepsy
E Gordon et al.
EPILEPSIA (2001)
Assessment of the role of CB1 receptors in cannabinoid anticonvulsant effects
MJ Wallace et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2001)
Activation of the CB1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicity
ME Abood et al.
NEUROSCIENCE LETTERS (2001)
Presynaptic specificity of endocannabinoid signaling in the hippocampus
RI Wilson et al.
NEURON (2001)
Endogenous cannabinoid as a retrograde messenger from depolarized postsynaptic neurons to presynaptic terminals
T Maejima et al.
NEUROSCIENCE RESEARCH (2001)
Blockade of effects of smoked marijuana by the CBl-selective cannabinoid receptor antagonist SR141716
MA Huestis et al.
ARCHIVES OF GENERAL PSYCHIATRY (2001)
Anticonvulsant activity of N-palmitoylethanolamide, a putative endocannabinoid, in mice
DM Lambert et al.
EPILEPSIA (2001)
Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells
AC Kreitzer et al.
NEURON (2001)
Incidence and risk factors in sudden unexpected death in epilepsy - A prospective cohort study
TS Walczak et al.
NEUROLOGY (2001)
The effects of adolescent cannabis use on educational attainment: a review
M Lynskey et al.
ADDICTION (2000)
The cannabinoid system and cytokine network
TW Klein et al.
PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE (2000)
Cannabinoid receptor ligands: clinical and neuropharmacological considerations, relevant to future drug discovery and development
RG Pertwee
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2000)
Early identification of refractory epilepsy.
P Kwan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)
Protein kinase-dependent phosphorylation and cannabinoid receptor modulation of potassium A current (I-A) in cultured rat hippocampal neurons
J Mu et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2000)
Is there a role for therapeutic drug monitoring of new anticonvulsants?
E Perucca
CLINICAL PHARMACOKINETICS (2000)