Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 47, Issue 8, Pages 2611-2615Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00278-09
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Funding
- Croatian Ministry of Science, Education, and Sports [143-1080116-0097, 143-0000000-0117]
- Slovenian Research Agency [Z3-0220-0381-08]
- Slovenian-Croatian Bilateral Project [BI-HR/09-10-017]
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A genotyping study of 285 Hybrid Capture 2 low-risk probe cocktail-positive specimens showed cross-reactivity with several untargeted human papillomavirus genotypes. Cross-reactivity was often clinically beneficial due to the detection of untargeted low-risk genotypes. A total of 8.4% of positive results, usually weak, were due to cross-reactivity with high-risk genotypes. Establishment of a gray zone is recommended.
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