4.7 Article

Bartonella sp bacteremia in patients with neurological and neurocognitive dysfunction

Journal

JOURNAL OF CLINICAL MICROBIOLOGY
Volume 46, Issue 9, Pages 2856-2861

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00832-08

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Funding

  1. State of North Carolina
  2. Sigmon Trust
  3. Bayer Animal Health
  4. IDEXX Laboratories
  5. Southeastern Center for Emerging Biological Threats

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We detected infection with a Bartonella species (B. henselae or B. vinsonii subsp. berkhoffii) in blood samples from six immunocompetent patients who presented with a chronic neurological or neurocognitive syndrome including seizures, ataxia, memory loss, and/or tremors. Each of these patients had substantial animal contact or recent arthropod exposure as a potential risk factor for Bartonella infection. Additional studies should be performed to clarify the potential role of Bartonella spp. as a cause of chronic neurological and neurocognitive dysfunction.

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