4.7 Article

Vancomycin heteroresistance in bloodstream isolates of Staphylococcus capitis

Journal

JOURNAL OF CLINICAL MICROBIOLOGY
Volume 46, Issue 9, Pages 3124-3126

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00592-08

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Funding

  1. School of Applied Sciences, RMIT University, Australia
  2. Department of Microbiology and Infectious Diseases, Royal Children's and Royal Women's Hospitals, Australia

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Nine Staphylococcus capitis isolates from blood cultures of newborns were examined for resistance to vancomycin. MICs were within the susceptible range, but population profiling revealed a resistant subpopulation. Only isolates with the largest subpopulation were identified as heteroresistant to vancomycin by Etest. This finding may have therapeutic implications.

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