Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 46, Issue 5, Pages 1881-1884Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.01875-07
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Funding
- NCRR NIH HHS [T32 RR007036] Funding Source: Medline
- PHS HHS [T32RRO7036] Funding Source: Medline
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Sentinel mouse. seroconversion to infectious agents is critical for laboratory animal facility disease monitoring. We report spontaneous emergence of non-sex-linked agammaglobulinemia with B-cell deficiency and cutaneous Staphylococcus aureus granulomatosis (botryomycosis) in a cohort of related Swiss Webster sentinel mice. Our experience reinforces the importance of immunocompetency validation in surveillance programs.
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