Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 46, Issue 6, Pages 2070-2073Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00203-08
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Funding
- NIAID
- NIH [N01-AI-30058]
- DHHS
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The rapid and accurate identification of Escherichia coli O157:H7 strains is central to reducing the impact of outbreaks. A real-time PCR-based approach to differentiating major outbreak lineages of O157 with novel single-nucleotide polymorphisms is described. The utility of this method is in detection of hypervirulent strains in cases of clinical disease.
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