Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 46, Issue 12, Pages 4075-4077Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00822-08
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Funding
- National High-Tech R&D Program ( 863) of China [2007AA02Z405]
- National Natural Science Foundation of China [30770030]
- China National Basic Research Program ( 973) [2006CB504401]
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Thirteen extensively drug-resistant tuberculosis isolates which were highly resistant to a broad spectrum of antituberculosis drugs were identified from 1,926 clinical isolates in China. They had highly diverse mycobacterial interspersed repetitive-unit-variable-number tandem-repeat patterns. Most, but not all, of the drug target genes had mutations contributing to resistance to the corresponding drug.
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