4.5 Article

Neutrophil-to-Lymphocyte Ratio Positively Correlates to Age in Healthy Population

Journal

JOURNAL OF CLINICAL LABORATORY ANALYSIS
Volume 29, Issue 6, Pages 437-443

Publisher

JOHN WILEY & SONS INC
DOI: 10.1002/jcla.21791

Keywords

clinical parameter; immunity; lymphocyte; neutrophil; NLR

Funding

  1. Province Natural Science Foundation of Guangdong, China [S2013010014007]
  2. Province Science and Technology Project Plan and Social Development of Guangdong, China [2010B030700007]

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Background: Neutrophil to lymphocyte ratio (NLR) was reported to be an independent easy-to-measure marker for many diseases, while the distribution of NLR in healthy population was not formally studied. So we investigated NLR in healthy people in this study. Methods: Data include NLR, systolic pressure, diastolic pressure, and body mass index (BMI), which were collected from 3,262 healthy population. Correlations of NLR with variables were analyzed with SPSS16.0. Results: Results demonstrated that NLR was positively associated with age (P < 0.001). The eldest age group possessed the highest NLR and the youngest age group had the lowest NLR. NLR was also slightly positively associated with systolic pressure, diastolic pressure, and BMI (P < 0.001). Conclusion: Older people possessed relatively high NLR in healthy population. (C) 2014 Wiley Periodicals, Inc.

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