Related references
Note: Only part of the references are listed.Development and Quantitative Evaluation of a High-Resolution Metabolomics Technology
Xiaojing Liu et al.
ANALYTICAL CHEMISTRY (2014)
Dichloroacetate should be considered with platinum-based chemotherapy in hypoxic tumors rather than as a single agent in advanced non-small cell lung cancer
Edward B. Garon et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2014)
Metabolic Reprogramming Is Required for Antibody Production That Is Suppressed in Anergic but Exaggerated in Chronically BAFF-Exposed B Cells
Alfredo Caro-Maldonado et al.
JOURNAL OF IMMUNOLOGY (2014)
Attenuation of Experimental Colitis in Glutathione Peroxidase 1 and Catalase Double Knockout Mice through Enhancing Regulatory T Cell Function
Hyung-Ran Kim et al.
PLOS ONE (2014)
Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
Chih-Hao Chang et al.
CELL (2013)
Acylcarnitines Reflecting or Inflicting Insulin Resistance?
Marieke G. Schooneman et al.
DIABETES (2013)
Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling
Laura A. Sena et al.
IMMUNITY (2013)
Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function
Madhusudhanan Sukumar et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Ablation of Peroxiredoxin II Attenuates Experimental Colitis by Increasing FoxO1-Induced Foxp3+ Regulatory T Cells
Hee Yeon Won et al.
JOURNAL OF IMMUNOLOGY (2013)
A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence
Joanna Kaplon et al.
NATURE (2013)
Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity
Yoko Kidani et al.
NATURE IMMUNOLOGY (2013)
Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation
Linda V. Sinclair et al.
NATURE IMMUNOLOGY (2013)
Dichloroacetate induces protective autophagy in LoVo cells: involvement of cathepsin D/thioredoxin-like protein 1 and Akt-mTOR-mediated signaling
F. Gong et al.
CELL DEATH & DISEASE (2013)
Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology
Gopinath Sutendra et al.
FRONTIERS IN ONCOLOGY (2013)
The role of low-level lactate production in airway inflammation in asthma
Marina Ostroukhova et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2012)
The IL-17 Differentiation Pathway and Its Role in Transplant Outcome
Jonathan S. Serody et al.
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2012)
Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development
Gerritje J. W. van der Windt et al.
IMMUNITY (2012)
NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis
Makoto Inoue et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Increased thioredoxin-1 production in human naturally occurring regulatory T cells confers enhanced tolerance to oxidative stress
Dimitrios Mougiakakos et al.
BLOOD (2011)
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
Eric V. Dang et al.
CELL (2011)
The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
Ruoning Wang et al.
IMMUNITY (2011)
HIF1α-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
Lewis Z. Shi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
Ryan D. Michalek et al.
JOURNAL OF IMMUNOLOGY (2011)
Tyrosine Phosphorylation of Mitochondrial Pyruvate Dehydrogenase Kinase 1 Is Important for Cancer Metabolism
Taro Hitosugi et al.
MOLECULAR CELL (2011)
Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation
Ryan D. Michalek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Differentiation of Effector CD4 T Cell Populations
Jinfang Zhu et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 28 (2010)
Reversal of the glycolytic phenotype by dichloroacetate inhibits metastatic breast cancer cell growth in vitro and in vivo
Ramon C. Sun et al.
BREAST CANCER RESEARCH AND TREATMENT (2010)
Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC
Luke H. Stockwin et al.
INTERNATIONAL JOURNAL OF CANCER (2010)
Metabolic Modulation of Glioblastoma with Dichloroacetate
E. D. Michelakis et al.
SCIENCE TRANSLATIONAL MEDICINE (2010)
Mechanisms of impaired regulation by CD4+CD25+FOXP3+ regulatory T cells in human autoimmune diseases
Jane Hoyt Buckner
NATURE REVIEWS IMMUNOLOGY (2010)
Naturally occurring regulatory T cells show reduced sensitivity toward oxidative stress-induced cell death
Dimitrios Mougiakakos et al.
BLOOD (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Dichloroacetate alleviates development of collagen II-induced arthritis in female DBA/1 mice
Li Bian et al.
ARTHRITIS RESEARCH & THERAPY (2009)
Glucose uptake is limiting in T cell activation and requires CD28-mediated akt-dependent and independent pathways
Sarah R. Jacobs et al.
JOURNAL OF IMMUNOLOGY (2008)
Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival
Nancie J. MacIver et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2008)
Distinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicol
Masato Kato et al.
STRUCTURE (2007)
The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells
Ivaylo I. Ivanov et al.
CELL (2006)
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
D Yen et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Piroxicam treatment of IL-10-deficient mice enhances colonic epithelial apoptosis and mucosal exposure to intestinal bacteria
LP Hale et al.
INFLAMMATORY BOWEL DISEASES (2005)
Fuel feeds function: Energy metabolism and the T-cell response
CJ Fox et al.
NATURE REVIEWS IMMUNOLOGY (2005)
Natural recovery and protection from autoimmune encephalomyelitis:: Contribution of CD4+CD25+ regulatory cells within the central nervous system
MJ McGeachy et al.
JOURNAL OF IMMUNOLOGY (2005)
Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance
J An et al.
NATURE MEDICINE (2004)
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
DJ Cua et al.
NATURE (2003)
The CD28 signaling pathway regulates glucose metabolism
KA Frauwirth et al.
IMMUNITY (2002)
Site specificity of four pyruvate dehydrogenase kinase isoenzymes toward the three phosphorylation sites of human pyruvate dehydrogenase
LG Korotchkina et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Share Paper
