Related references
Note: Only part of the references are listed.A senescent cell bystander effect: senescence-induced senescence
Glyn Nelson et al.
AGING CELL (2012)
The number of p16INK4a positive cells in human skin reflects biological age
Mariette E. C. Waaijer et al.
AGING CELL (2012)
Glucocorticoids suppress selected components of the senescence-associated secretory phenotype
Remi-Martin Laberge et al.
AGING CELL (2012)
Immune surveillance of senescent cells-biological significance in cancer- and non-cancer pathologies
Lisa Hoenicke et al.
CARCINOGENESIS (2012)
Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions
Anitha Suram et al.
EMBO JOURNAL (2012)
Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice
Alexander Rodriguez Guerrero et al.
JOURNAL OF NEUROINFLAMMATION (2012)
ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence
U. Weyemi et al.
ONCOGENE (2012)
Immune surveillance of pre-cancerous senescent hepatocytes limits hepatocellular carcinoma development
Tetyana Yevsa et al.
ONCOIMMUNOLOGY (2012)
Nuclear protein accumulation in cellular senescence and organismal aging revealed with a novel single-cell resolution fluorescence microscopy assay
Marco De Cecco et al.
AGING-US (2011)
Pancreatitis-Induced Inflammation Contributes to Pancreatic Cancer by Inhibiting Oncogene-Induced Senescence
Carmen Guerra et al.
CANCER CELL (2011)
Frailty Defined by Deficit Accumulation and Geriatric Medicine Defined by Frailty
Kenneth Rockwood et al.
CLINICS IN GERIATRIC MEDICINE (2011)
Cellular senescence: putting the paradoxes in perspective
Judith Campisi
CURRENT OPINION IN GENETICS & DEVELOPMENT (2011)
p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype
Adam Freund et al.
EMBO JOURNAL (2011)
Tumor Suppressor and Aging Biomarker p16INK4a Induces Cellular Senescence without the Associated Inflammatory Secretory Phenotype
Jean-Philippe Coppe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Four faces of cellular senescence
Francis Rodier et al.
JOURNAL OF CELL BIOLOGY (2011)
Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
Tae-Won Kang et al.
NATURE (2011)
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
Darren J. Baker et al.
NATURE (2011)
New insights into oncogenic stress
Kevin M. Haigis et al.
NATURE GENETICS (2011)
Fat tissue, aging, and cellular senescence
Tamara Tchkonia et al.
AGING CELL (2010)
Cellular senescence controls fibrosis in wound healing
Joon-Il Jun et al.
AGING-US (2010)
Adult-onset, short-term dietary restriction reduces cell senescence in mice
Chunfang Wang et al.
AGING-US (2010)
Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways
Aaron J. Schetter et al.
CARCINOGENESIS (2010)
With TOR, Less Is More: A Key Role for the Conserved Nutrient-Sensing TOR Pathway in Aging
Pankaj Kapahi et al.
CELL METABOLISM (2010)
Mechanisms by Which Inflammation May Increase Intestinal Cancer Risk in Inflammatory Bowel Disease
Pamela M. O'Connor et al.
INFLAMMATORY BOWEL DISEASES (2010)
Feedback between p21 and reactive oxygen production is necessary for cell senescence
Joao F. Passos et al.
MOLECULAR SYSTEMS BIOLOGY (2010)
The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing
Joon-Il Jun et al.
NATURE CELL BIOLOGY (2010)
A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen
Jean-Philippe Coppe et al.
PLOS ONE (2010)
Inflammatory networks during cellular senescence: causes and consequences
Adam Freund et al.
TRENDS IN MOLECULAR MEDICINE (2010)
Real-time in vivo imaging of p16Ink4a gene expression: a new approach to study senescence stress signaling in living animals
Naoko Ohtani et al.
CELL DIVISION (2010)
An index of self-rated health deficits in relation to frailty and adverse outcomes in older adults
Anna Lucicesare et al.
AGING CLINICAL AND EXPERIMENTAL RESEARCH (2010)
Molecular inflammation: Underpinnings of aging and age-related diseases
Hae Young Chung et al.
AGEING RESEARCH REVIEWS (2009)
MicroRNAs miR-146a/b negatively modulate the senescence associated inflammatory mediators IL-6 and IL-8
Dipa Bhaumik et al.
AGING-US (2009)
Inflammation, Coagulation, and the Pathway to Frailty
Bindu Kanapuru et al.
AMERICAN JOURNAL OF MEDICINE (2009)
Vulnerability to oxidative stress and different patterns of senescence in human peritoneal mesothelial cell strains
Krzysztof Ksiazek et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2009)
Decreased osteogenesis, increased cell senescence and elevated Dickkopf-1 secretion in human fracture non union stromal cells
Stefan Bajada et al.
BONE (2009)
A transcriptomic analysis of the EK1.Br strain of human fibroblastoid keratocytes: The effects of growth, quiescence and senescence
David Kipling et al.
EXPERIMENTAL EYE RESEARCH (2009)
Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults
Jeremy D. Walston et al.
EXPERIMENTAL GERONTOLOGY (2009)
Healthspan, Translation, and New Outcomes for Animal Studies of Aging
James L. Kirkland et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2009)
Nonlinear Multisystem Physiological Dysregulation Associated With Frailty in Older Women: Implications for Etiology and Treatment
Linda P. Fried et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2009)
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion
Francis Rodier et al.
NATURE CELL BIOLOGY (2009)
A crucial role for adipose tissue p53 in the regulation of insulin resistance
Tohru Minamino et al.
NATURE MEDICINE (2009)
Upregulated ex vivo expression of stress-responsive inflammatory pathway genes by LPS-challenged CD14+ monocytes in frail older adults
Tao Qu et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2009)
Cell surface-bound IL-1α is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network
Arturo V. Orjalo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Measuring Systemic Inflammatory Regulation in Older Adults: Evidence and Utility
Karen Bandeen-Roche et al.
REJUVENATION RESEARCH (2009)
Associations of Depression With C-Reactive Protein, IL-1, and IL-6: A Meta-Analysis
M. Bryant Howren et al.
PSYCHOSOMATIC MEDICINE (2009)
Proteinopathy-induced neuronal senescence: a hypothesis for brain failure in Alzheimer's and other neurodegenerative diseases
Todd E Golde et al.
Alzheimers Research & Therapy (2009)
Endogenous Damage-Associated Molecular Pattern Molecules at the Crossroads of Inflammation and Cancer
Geetha Srikrishna et al.
NEOPLASIA (2009)
Unexpected pieces to the senescence puzzle
Karen Cichowski et al.
CELL (2008)
Senescence of activated stellate cells limits liver fibrosis
Valery Krizhanovsky et al.
CELL (2008)
Cellular senescence in vivo:: a barrier to tumorigenesis
Alexandre Prieur et al.
CURRENT OPINION IN CELL BIOLOGY (2008)
Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency
Darren J. Baker et al.
NATURE CELL BIOLOGY (2008)
Cellular senescence and organismal aging
Jessie C. Jeyapalan et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2008)
Many roads lead to oncogene-induced senescence
S. Courtois-Cox et al.
ONCOGENE (2008)
The wolf in sheep's clothing: the role of interieukin-6 in immunity, inflammation and cancer
Willscott E. Naugler et al.
TRENDS IN MOLECULAR MEDICINE (2008)
Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
Jean-Philippe Coppe et al.
PLOS BIOLOGY (2008)
Cellular senescence in endothelial cells from atherosclerotic patients is accelerated by oxidative stress associated with cardiovascular risk factors
Guillaume Voghel et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2007)
Cellular senescence in cancer and aging
Manuel Collado et al.
CELL (2007)
Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis
Brooke Ancrile et al.
GENES & DEVELOPMENT (2007)
Inflammation and frailty in older women
Sean X. Leng et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2007)
Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion
Dan Liu et al.
CANCER RESEARCH (2007)
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
Wen Xue et al.
NATURE (2007)
Inflammatory networks in ageing, age-related diseases and longevity
Sonya Vasto et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2007)
Accumulation of senescent cells in mitotic tissue of aging primates
Jessie C. Jeyapalan et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2007)
Inflammaging and anti-inflammaging: A systemic perspective on aging and longevity emerged from studies in humans
Claudio Franceschi et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2007)
Cellular senescence: when bad things happen to good cells
Judith Campisi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Research agenda for frailty in older adults: Toward a better understanding of physiology and etiology: Summary from the American Geriatrics Society/National institute on aging research conference on frailty in older adults
Jeremy Walston et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2006)
Long-term risks of death and institutionalization of elderly people in relation to deficit accumulation at age 70
Kenneth Rockwood et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2006)
Oncogene-induced senescence: Putting the brakes on tumor development
M Braig et al.
CANCER RESEARCH (2006)
Cellular senescence in aging primates
U Herbig et al.
SCIENCE (2006)
Phenotype of frailty: Characterization in the women's health and aging studies
K Bandeen-Roche et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2006)
The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor
S Gasser et al.
NATURE (2005)
Oncogene-induced senescence as an initial barrier in lymphoma development
M Braig et al.
NATURE (2005)
Leukocyte count as a predictor of cardiovascular events and mortality in postmenopausal women
KL Margolis et al.
ARCHIVES OF INTERNAL MEDICINE (2005)
Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
J Campisi
CELL (2005)
Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation
S Parrinello et al.
JOURNAL OF CELL SCIENCE (2005)
Inflammatory markers and risk of developing type 2 diabetes in women
FB Hu et al.
DIABETES (2004)
What can progeroid syndrome tell us about human aging?
D Kipling et al.
SCIENCE (2004)
Inflammatory markers and the risk of coronary heart disease in men and women.
JK Pai et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Loss of proliferative capacity and induction of senescence in oxidatively stressed human fibroblasts
JH Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis
A Sparmann et al.
CANCER CELL (2004)
Inflammatory markers and cardiovascular disease (The Health, Aging and Body Composition [Health ABC] Study)
M Cesari et al.
AMERICAN JOURNAL OF CARDIOLOGY (2003)
Elevated levels of tumor necrosis factor alpha and mortality in centenarians
H Bruunsgaard et al.
AMERICAN JOURNAL OF MEDICINE (2003)
Inflammatory cytokines and the risk to develop type 2 diabetes -: Results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study
J Spranger et al.
DIABETES (2003)
Aging and genome maintenance: Lessons from the mouse?
P Hasty et al.
SCIENCE (2003)
Age-related inflammatory cytokines and disease
H Brüünsgaard et al.
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA (2003)
Innate inhibition of adaptive immunity: Mycobacterium tuberculosis-induced IL-6 inhibits macrophage responses to IFN-gamma
V Nagabhushanam et al.
JOURNAL OF IMMUNOLOGY (2003)
Frailty and activation of the inflammation and coagulation systems with and without clinical comorbidities - Results from the Cardiovascular Health Study
J Walston et al.
ARCHIVES OF INTERNAL MEDICINE (2002)
The role of chondrocyte senescence in osteoarthritis
JS Price et al.
AGING CELL (2002)
Interleukin-6 causes endothelial barrier dysfunction via the protein kinase C pathway
TR Desai et al.
JOURNAL OF SURGICAL RESEARCH (2002)
Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice
P Krimpenfort et al.
NATURE (2001)
C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus
AD Pradhan et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2001)
White blood cell count: An independent predictor of coronary heart disease mortality among a national cohort
DW Brown et al.
JOURNAL OF CLINICAL EPIDEMIOLOGY (2001)
Frailty in older adults: Evidence for a phenotype
LP Fried et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2001)
Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part I - effects of proliferative senescence
N Sitte et al.
FASEB JOURNAL (2000)