4.8 Editorial Material

Epithelial-mesenchymal transitions and hepatocarcinogenesis

Journal

JOURNAL OF CLINICAL INVESTIGATION
Volume 120, Issue 4, Pages 1031-1034

Publisher

AMER SOC CLINICAL INVESTIGATION INC
DOI: 10.1172/JCI42615

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Funding

  1. NIAAA NIH HHS [R01 AA01054] Funding Source: Medline
  2. NIDDK NIH HHS [R01 DK077794] Funding Source: Medline

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Epithelial-mesenchymal transitions (EMTs) are believed to play a role in invasion and metastasis of many types of tumors. In this issue of the JCI, Chen et al. show that a gene that has been associated with aggressive biology in hepatocellular carcinomas initiates a molecular cascade that results in EMT.

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