Related references
Note: Only part of the references are listed.Exercise-induced alterations in intramyocellular lipids and insulin resistance:: the athlete's paradox revisited
John J. Dube et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
Intramuscular lipid oxidation and obesity
Joseph A. Houmard
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2008)
Direct monitoring of in vivo ER stress during the development of insulin resistance with ER stress-activated indicator transgenic mice
Kazutomi Yoshiuchi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
Timothy R. Koves et al.
CELL METABOLISM (2008)
Fast/glycolytic muscle fiber growth reduces fat mass and improves metabolic parameters in obese mice
Yasuhiro Izumiya et al.
CELL METABOLISM (2008)
Asian Indians have enhanced skeletal muscle mitochondrial capacity to produce ATP in association with severe insulin resistance
K. Sreekumaran Nair et al.
DIABETES (2008)
Macrophage chemoattractant protein-1 deficiency fails to restrain macrophage infiltration into adipose tissue
Elizabeth A. Kirk et al.
DIABETES (2008)
The role for endoplasmic reticulum stress in diabetes mellitus
Decio L. Eizirik et al.
ENDOCRINE REVIEWS (2008)
The secretory function of adipocytes in the physiology of white adipose tissue
Ping Wang et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2008)
Inflammation and insulin resistance
Carl de Luca et al.
FEBS LETTERS (2008)
Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes
Bohan Wang et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2007)
Adipocyte death, adipose tissue remodeling, and obesity complications
Katherine J. Strissel et al.
DIABETES (2007)
SIRT1 transgenic mice show phenotypes resembling calorie restriction
Laura Bordone et al.
AGING CELL (2007)
A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via toll-like receptors 2 and 4 and JNK-dependent pathways
M. T. Audrey Nguyen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
Jill C. Milne et al.
NATURE (2007)
Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes
J. Andrew Pospisilik et al.
CELL (2007)
JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity
Giovanni Solinas et al.
CELL METABOLISM (2007)
Salicylate prevents hepatic insulin resistance caused by short-term elevation of free fatty acids in vivo
Edward Park et al.
JOURNAL OF ENDOCRINOLOGY (2007)
Role of low energy expenditure and sitting in obesity, metabolic syndrome, type 2 diabetes, and cardiovascular disease
Marc T. Hamilton et al.
DIABETES (2007)
Abnormal glucose homeostasis in skeletal muscle-specific PGC-1α knockout mice reveals skeletal muscle-pancreatic β cell crosstalk
Christoph Handschin et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice
Jianping Ye et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B
Cheng Sun et al.
CELL METABOLISM (2007)
Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice
Takashi Nomiyama et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Deficiency of Cbl-b gene enhances infiltration and activation of macrophages in adipose tissue and causes peripheral insulin resistance in mice
Katsuya Hirasaka et al.
DIABETES (2007)
Obesity-associated improvements in metabolic profile through expansion of adipose tissue
Ja-Young Kim et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Macrophage TNF-α contributes to insulin resistance and hepatic steatosis in diet-induced obesity
Bart M. De Taeye et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
PPARγ activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties
M. Amine Bouhlel et al.
CELL METABOLISM (2007)
被撤回的出版物: Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance (Retracted article. See vol. 65, pg. 1126, 2016)
Daniela M. L. Tsukumo et al.
DIABETES (2007)
Signal integration in the endoplasmic reticulum unfolded protein response
David Ron et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver
Mara Monetti et al.
CELL METABOLISM (2007)
Metabolic endotoxemia initiates obesity and insulin resistance
Patrice D. Cani et al.
DIABETES (2007)
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
Justin I. Odegaard et al.
NATURE (2007)
Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance
Simon Schenk et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance
Li Liu et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
The mammalian target of rapamycin pathway regulates nutrient-sensitive glucose uptake in man
Michael Krebs et al.
DIABETES (2007)
Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
Andrea L. Hevener et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Class IA phosphoinositide 3-kinases are obligate p85-p110 heterodimers
Barbara Geering et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Obesity, inflammation, and insulin resistance
Steven E. Shoelson et al.
GASTROENTEROLOGY (2007)
Patients with type 2 diabetes have normal mitochondrial function in skeletal muscle
R. Boushel et al.
DIABETOLOGIA (2007)
Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance
William L. Holland et al.
CELL METABOLISM (2007)
Calorie restriction increases muscle mitochondrial biogenesis in healthy humans
Anthony E. Civitarese et al.
PLOS MEDICINE (2007)
Adipocyte stress: the endoplasmic reticulum and metabolic disease
Margaret F. Gregor et al.
JOURNAL OF LIPID RESEARCH (2007)
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
Carey N. Lumeng et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity
Carey N. Lumeng et al.
DIABETES (2007)
Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation
Naomi Hosogai et al.
DIABETES (2007)
Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue
Karen E. Inouye et al.
DIABETES (2007)
Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction
Katsutaro Morino et al.
DIABETES (2006)
TLR4 links innate immunity and fatty acid-induced insulin resistance
Hang Shi et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
Umut Oezcan et al.
SCIENCE (2006)
Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects
Gautam K. Bandyopadhyay et al.
DIABETES (2006)
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
Hajime Kanda et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Signaling functions of phosphatidic acid
Xuemin Wang et al.
PROGRESS IN LIPID RESEARCH (2006)
Prevalence of overweight and obesity in the United States, 1999-2004
CL Ogden et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2006)
Nutritional upregulation of p85α expression is an early molecular manifestation of insulin resistance
MA Cornier et al.
DIABETOLOGIA (2006)
Tissue-specific roles of IRS proteins in insulin signaling and glucose transport
ACP Thirone et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2006)
Critical nodes in signalling pathways: insights into insulin action
CM Taniguchi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
SP Weisberg et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation
A Tzatsos et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Specific protein kinase C isoforms as transducers and modulators of insulin signaling
Sanford R. Sampson et al.
MOLECULAR GENETICS AND METABOLISM (2006)
Effect of a sustained reduction in plasma free fatty acid concentration on intramuscular long-chain fatty acyl-CoAs and insulin action in type 2 diabetic patients
M Bajaj et al.
DIABETES (2005)
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
S Cinti et al.
JOURNAL OF LIPID RESEARCH (2005)
JNK and tumor necrosis factor-α mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes
MTA Nguyen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Lysophosphatidic acid mediates pleiotropic responses in skeletal muscle cells
G Jean-Baptiste et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Differential expression of inflammatory chemokines by Th1- and Th2-cell promoting dendritic cells: A role for different mature dendritic cell populations in attracting appropriate effector cells to peripheral sites of inflammation
MC Lebre et al.
IMMUNOLOGY AND CELL BIOLOGY (2005)
Increased p85/55/50 expression and decreased phosphotidylinositol 3-kinase activity in insulin-resistant human skeletal muscle
GK Bandyopadhyay et al.
DIABETES (2005)
Diet induction of monocyte chemoattractant protein-1 and its impact on obesity
AR Chen et al.
OBESITY RESEARCH (2005)
Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-α and interleukin-6
YK Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Calorie restriction increases the ratio of phosphatidylinositol 3-kinase catalytic to regulatory subunits in rat skeletal muscle
CE McCurdy et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)
Type 2 diabetes: principles of pathogenesis and therapy
M Stumvoll et al.
LANCET (2005)
Changes in insulin resistance following bariatric surgery: Role of caloric restriction and weight loss
AA Gumbs et al.
OBESITY SURGERY (2005)
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
DS Cai et al.
NATURE MEDICINE (2005)
IKK-β links inflammation to obesity-induced insulin resistance
MC Arkan et al.
NATURE MEDICINE (2005)
Positive and negative regulation of insulin signaling through IRS-1 phosphorylation
P Gual et al.
BIOCHIMIE (2005)
Enzymes of triacylglycerol synthesis and their regulation
RA Coleman et al.
PROGRESS IN LIPID RESEARCH (2004)
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
SH Um et al.
NATURE (2004)
AMP-activated protein kinase is not down-regulated in human skeletal muscle of obese females
GR Steinberg et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
PKC-θ knockout mice are protected from fat-induced insulin resistance
JK Kim et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
FR Greten et al.
CELL (2004)
The chemokine system in diverse forms of macrophage activation and polarization
A Mantovani et al.
TRENDS IN IMMUNOLOGY (2004)
Increased β-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation
G Perdomo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
P50 alpha/p55 alpha phosphoinositide 3-kinase knockout mice exhibit enhanced insulin sensitivity
D Chen et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
U Özcan et al.
SCIENCE (2004)
Reciprocal modulation of toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids
JY Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes:: Potential role of PGC1 and NRF1
ME Patti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
VK Mootha et al.
NATURE GENETICS (2003)
Obesity is associated with macrophage accumulation in adipose tissue
SP Weisberg et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
HY Xu et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Minireview: Nutrient sensing and the regulation of insulin action and energy balance
S Obici et al.
ENDOCRINOLOGY (2003)
Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001
AH Mokdad et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2003)
Obesity - is it a genetic disorder?
RJF Loos et al.
JOURNAL OF INTERNAL MEDICINE (2003)
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
CL Yu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Activation of the Drosophila MLK by ceramide reveals TNF-α and ceramide as agonists of mammalian MLK3
P Sathyanarayana et al.
MOLECULAR CELL (2002)
A central role for JNK in obesity and insulin resistance
J Hirosumi et al.
NATURE (2002)
Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IκB-α
SI Itani et al.
DIABETES (2002)
Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action
V Aguirre et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Effects of fatty acids on exercise plus insulin-induced glucose utilization in trained and sedentary subjects
O Matzinger et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)
Overfeeding rapidly induces leptin and insulin resistance
JL Wang et al.
DIABETES (2001)
Skeletal muscle lipid content and insulin resistance: Evidence for a paradox in endurance-trained athletes
BH Goodpaster et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2001)
Insulin resistance in obesity: body-weight or energy balance?
AR Assali et al.
JOURNAL OF ENDOCRINOLOGY (2001)
Effects of intravenous and dietary lipid challenge on intramyocellular lipid content and the relation with insulin sensitivity in humans
OP Bachmann et al.
DIABETES (2001)
Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of IKKβ
MS Yuan et al.
SCIENCE (2001)
Insulin resistance as a predictor of age-related diseases
FS Facchini et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2001)
Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4
JY Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Ceramide dissociates 3′-phosphoinositide production from pleckstrin homology domain translocation
S Stratford et al.
BIOCHEMICAL JOURNAL (2001)
Oxidative stress and gene expression: The AP-1 and NF-kappa B connections
M Karin et al.
BIOFACTORS (2001)
Share Paper
