Related references
Note: Only part of the references are listed.Mutations to Ku reveal differences in human somatic cell lines
Kazi R. Fattah et al.
DNA REPAIR (2008)
The catalytic subunit of DNA-dependent protein kinase regulates proliferation, telomere length, and genomic stability in human somatic cells
Brian L. Ruis et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Lymphocyte-specific compensation for XLF/Cernunnos end-joining functions in V(D)J recombination
Gang Li et al.
MOLECULAR CELL (2008)
Non-homologous end-joining, a sticky affair
D. C. van Gent et al.
ONCOGENE (2007)
Defective artemis nuclease is characterized by coding joints with microhomology in long palindromic-nucleotide stretches
MirJarn Van der Burg et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
trans Autophosphorylation at DNA-dependent protein kinase's two major autophosphorylation site clusters facilitates end processing but not end joining
Katheryn Meek et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks
Naoya Uematsu et al.
JOURNAL OF CELL BIOLOGY (2007)
Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break
Benjamin P. C. Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The DNA-dependent protein kinase catalytic subunit is phosphorylated in vivo on threonine 3950, a highly conserved amino acid in the protein kinase domain
Pauline Douglas et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4
Pierre-Olivier Mari et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
DNA-PK autophosphorylation facilitates Artemis endonuclease activity
Aaron A. Goodarzi et al.
EMBO JOURNAL (2006)
Three-dimensional structure of the human DNA-PKcs/Ku70/Ku80 complex assembled on DNA and its implications for DNA DSB repair
Laura Spagnolo et al.
MOLECULAR CELL (2006)
XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining
P Ahnesorg et al.
CELL (2006)
Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly
D Buck et al.
CELL (2006)
A new type of radiosensitive T-B-NK+ severe combined immunodeficiency caused by a LIG4 mutation
M van der Burg et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Autophosphorylation of DNA-dependent protein kinase regulates DNA end processing and may also alter double-strand break repair pathway choice
XP Cui et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells
KJ McManus et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Mesoscale conformational changes in the DNA-repair complex Rad50/Mre11/Nbs1 upon binding DNA
F Moreno-Herrero et al.
NATURE (2005)
Specific association of mouse MDC1/NFBD1 with NBS1 at sites of DNA-damage
AC Lee et al.
CELL CYCLE (2005)
An overview of three new disorders associated with genetic instability: LIG4 syndrome, RS-SCID and ATR-Seckel syndrome
M O'Driscoll et al.
DNA REPAIR (2004)
Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries
JJJ Leahy et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
I Hickson et al.
CANCER RESEARCH (2004)
The mechanism of non-homologous end-joining: a synopsis of synapsis
E Weterings et al.
DNA REPAIR (2004)
Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX
IM Ward et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Defective DNA repair and increased genomic instability in artemis-deficient murine cells
S Rooney et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow
JG Noordzij et al.
BLOOD (2003)
Repair of DNA double strand breaks by non-homologous end joining
SP Lees-Miller et al.
BIOCHIMIE (2003)
A founder mutation in Artemis, an SNM1-like protein, causes SCID in Athabascan-speaking Native Americans
LY Li et al.
JOURNAL OF IMMUNOLOGY (2002)
Autosomal recessive severe combined immunodeficiency of Jack Russell Terriers
TG Bell et al.
JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION (2002)
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination
YM Ma et al.
CELL (2002)
Ku86 is essential in human somatic cells
G Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
DNA ligase IV mutations identified in patients exhibiting developmental delay and immunodeficiency
M O'Driscoll et al.
MOLECULAR CELL (2001)
Precursor-B-ALL with DH-JH gene rearrangements have an immature immunogenotype with a high frequency of oligoclonality and hyperdiploidy of chromosome 14
T Szczepanski et al.
LEUKEMIA (2001)
SCID in Jack Russell terriers: A new animal model of DNA-PKcs deficiency
K Meek et al.
JOURNAL OF IMMUNOLOGY (2001)
Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency
D Moshous et al.
CELL (2001)
How to make ends meet in V(D)J recombination
U Grawunder et al.
CURRENT OPINION IN IMMUNOLOGY (2001)