Journal
JOURNAL OF CLINICAL GASTROENTEROLOGY
Volume 43, Issue 4, Pages 342-349Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MCG.0b013e31818a3854
Keywords
acute liver failure; drug toxicity; liver transplantation
Categories
Ask authors/readers for more resources
Acetaminophen-induced hepatotoxicity is a common consequence of acetaminophen overdose and may lead to acute liver failure (ALF). Currently acetaminophen is the most common cause of ALF in both United States and United Kingdom, with a trend to increasing incidence in the United States. N-acetylcysteine is the most effective drug to prevent progression to liver failure with acetaminophen hepatotoxicity. Liver transplantation is the only definitive therapy that will significantly increase the chances of survival for advanced ALF. This communication reviews Current information regarding causes and management of acetaminophen-induced hepatotoxicity and ALF.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available