Journal
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY
Volume 32, Issue 7, Pages 767-774Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/13803390903521000
Keywords
Executive function; Mild traumatic brain injury; Postconcussion syndrome; Head injury; Diffusion tensor imaging; Neuropsychological assessment; Frontal lobes; Mesencephalon; Cognitive performance; Reaction time
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In order to improve detection of subtle cognitive dysfunction and to shed light on the etiology of persistent symptoms after mild-to-moderate traumatic brain injury (TBI), we employed an experimental executive reaction time (RT) test, standardized neuropsychological tests, and diffusion tensor imaging (DTI). The Executive RT-Test, an Executive Composite Score from standardized neuropsychological tests, and DTI-indices in the midbrain differentiated between patients with persistent symptoms from those fully recovered after mild-to-moderate TBI. We suggest that persistent symptoms in mild-to-moderate TBI may reflect disrupted fronto-striatal network involved in executive functioning, and the Executive RT-Test provides an objective and novel method to detect it.
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