Journal
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
Volume 866, Issue 1-2, Pages 154-166Publisher
ELSEVIER
DOI: 10.1016/j.jchromb.2008.01.058
Keywords
airway surface fluid; sputum; synovial fluid; amniotic fluid; saliva; cerebrospinal fluid; aqueous humor; vitreous humor; sweat; capillary electrophoresis; micellar electrokinetic capillary; chromatography; direct sample injection
Ask authors/readers for more resources
The analysis by capillary electrophoresis of less commonly analyzed biofluids is reviewed. The sample matrices considered include airway surface fluid, sputum, synovial fluid, amniotic fluid, saliva, cerebrospinal fluid, aqueous humor, vitreous humor, and sweat. Many of the techniques used in the analysis of abundant and commonly tested biofluids such as plasma or urine can be applied to these other matrices, e.g. sample extraction prior to analysis. However, for some of these alternative biofluids the available sample amounts are only in the nanoliter or low microliter range, which places constraints on the sample preparation options which are available. For such samples, direct sample injection may be necessary, possibly coupled with on-capillary concentration or derivatization approaches. Particular attention is paid in this review to analyses where the sample is directly injected onto the separation capillary or where minimal sample preparation is performed. (C) 2008 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available