Journal
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
Volume 876, Issue 1, Pages 97-102Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jchromb.2008.10.028
Keywords
Thermo-responsive polymer; Poly(N-isopropylacrylamide); Magnetic particle; Magnetic field inductive heating; Liquid chromatography; Packing material
Funding
- Japan Science and Technology Agency (JST)
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In this study, we examined the feasibility of a novel liquid chromatography technique that combines temperature-responsive polymeric materials with inductive heating via an alternating magnetic field (AMF). We considered the following components of the technique: (i) the preparation of composite materials of magnetite and silica, (ii) their heating behavior under the AMF, (iii) the conjugation of temperature-responsive polymers for the packing materials, and (iv) the elution profiles of the model Compounds in the AMF. The results showed that we Could influence the elution of the model Compounds by AMF induction heating generated by the surrounding coil. (C) 2008 Elsevier B.V. All rights reserved.
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