Journal
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
Volume 862, Issue 1-2, Pages 15-42Publisher
ELSEVIER
DOI: 10.1016/j.jchromb.2007.11.040
Keywords
heterocyclic aromatic amines; foods; extraction methods; chromatographic methods/mass spectrometry; capillary electrophoresis
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Analytical aspects concerning the heterocyclic aromatic amines (HAAs) determination in foods are reviewed. Sample pre-treatment procedures such as liquid-liquid extraction (LLE), supercritical fluid extraction, solid-phase extraction (SPE), solid-phase microextraction (SPME), and the mainly used LLE-SPE tandem extraction are discussed. The analytical methods used for the identification and quantification are HPLC, HPLC combined with single or tandem MS detection (HPLC-MS, HPLC-MS/MS), GC-MS and capillary electrophoresis. Advantages and figures of merit for each technique are discussed. (c) 2007 Elsevier B.V. All rights reserved.
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