Journal
JOURNAL OF CHROMATOGRAPHY A
Volume 1324, Issue -, Pages 49-56Publisher
ELSEVIER
DOI: 10.1016/j.chroma.2013.11.017
Keywords
Phthalic acid esters (PAEs); Liquid chromatography tandem mass; spectrometry (LC-MS/MS; Foodstuff; QuEChERS; SPE
Funding
- National Key Technology R&D Program of the Ministry of Science and Technology [2012BAK08B01]
- Fujian Provincial Department of Science and Technology [2012N0028]
- Shanghai Science and Technology Program, China [13DZ0502502]
Ask authors/readers for more resources
A rapid and sensitive method was developed for the determination of 23 phthalates in food samples including milk-based products, distilled liquor, wine, beverage, grain, meat, oil, biscuit (cookie), and canned food by liquid chromatography tandem mass spectrometry (LC-MS/MS). Liquid samples were exacted by acetonitrile, while solid samples were prepared by QuEChERS or glass-based SPE methods. The 23 phthalates were separated on Poroshell 120 EC-C-18 column and followed by positive electrospray ionization as well as multi-reaction monitoring provided by a triple-quadrupole tandem mass spectrometer. To reduce contamination, the plastic materials were avoided in sample handling and preparation. The LODs were between 0.8 and 15 mu g kg(-1) and LOQs were between 10 and 100 mu g kg(-1). By using different concentrations: 100, 500, and 1000 mu g kg(-1)) for DINP and DIDP; 50, 100, and 1000 mu g kg(-1) for other 21 phthalate compounds, the spiked recoveries were within 75.5-115.2% and the relative standard deviations (RSDs) were in the range of 3.2-18.9%. The proposed protocol was then applied to the analysis of 623 real samples collected from the two sides of the Taiwan Straits, and the DEHP was found in almost all samples tested in this study, with levels ranging from 0.02 to 2685 mg kg(-1). The present study demonstrated a rapid, sensitive, and accurate method for determining 23 phthalates in foodstuffs. (C) 2013 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available