Journal
JOURNAL OF CHROMATOGRAPHY A
Volume 1216, Issue 11, Pages 2033-2044Publisher
ELSEVIER
DOI: 10.1016/j.chroma.2008.07.026
Keywords
Traditional Chinese medicines (TCMs); Quality control; Qualitative analysis; Quantitative analysis; Fingerprint analysis
Funding
- Knowledge Innovation Program of DICR CAS [K2006A3, K2006A4]
- Ministry of Science & Technology of China [2006BA106A01-06]
- Science and Technology plan of Liaoning Province [2006226002]
- Project of International Cooperation Plan from Ministry of Science and Technology of China [20071816]
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Separation techniques with high efficiency and sensitive detection have been widely used for quality control of traditional Chinese medicines (TCMs). High-performance liquid chromatography, gas chromatography, and capillary electrophoresis are commonly Used to separate various components in TCMs. Ultraviolet detection, fluorescence detection, evaporative light-scattering detection, mass spectrometry and nuclear magnetic resonance can be applied to separation techniques for qualitative and quantitative analysis of TCMs. The development of quality control for TCMs based on quantitative and qualitative analysis from 2000 to 2007 are reviewed; the fingerprint technique is also discussed due to its broad application in the quality control of TCMs. Prospects for further research based on our primary results are also discussed. (C) 2008 Elsevier B.V. All rights reserved.
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