Journal
JOURNAL OF CHILD NEUROLOGY
Volume 24, Issue 4, Pages 477-477Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/0883073808324535
Keywords
tuberous sclerosis; rapamycin; seizures
Categories
Funding
- NCRR NIH HHS [KL2 RR024149, KL2 RR024149-05S1] Funding Source: Medline
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The authors present a 10-year-old girl with tuberous sclerosis complex who has been receiving rapamycin for 10 months for seizure control. She was started at 0.05 mg/kg/d and titrated to an effective dose of 0.15 mg/kg/d. There was it dramatic reduction in seizure frequency with rapamycin therapy. Further studies are needed to objectively investigate the benefits of rapamycin in tuberous sclerosis complex and to clarify its mechanism of seizure control.
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