4.1 Article

Angiocentric Glioma-Induced Seizures in a 2-Year-Old Child

Journal

JOURNAL OF CHILD NEUROLOGY
Volume 24, Issue 7, Pages 852-856

Publisher

SAGE PUBLICATIONS INC
DOI: 10.1177/0883073808331078

Keywords

angiocentric glioma; symptomatic partial epilepsy; functional mapping; epilepsy surgery; brain tumor

Funding

  1. National Institute of Health (NIH)
  2. Shainberg Foundation
  3. University of Tennessee Neuroscience Institute
  4. UCB Inc
  5. Ovation
  6. Questcor
  7. Marinus
  8. Ortho-McNeil
  9. King Pharmaceuticals
  10. Cyberonics

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A 2-year-old child presented with medically refractory seizures and was found to have a right frontoparietal parasagittal angiocentric glioma. Depth electrodes were used to document ictal onset from within the tumor rather than from the Surrounding tissues. Ictal activity then spread to a wide area on the cortical Surface, including the region around the tumor and hand motor cortex. Lesionectomy permitted sparing of adjacent areas of eloquent cortex, and the child is now seizure-free on monotherapy.

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